Common Supplements and Drug Interactions
By Greta Jenkins –
If you take some common supplements along with prescription medications you may be canceling out the effect of your prescriptions, or even putting yourself at risk of serious side effects. We listed a few of the common supplements and prescription drug interactions. Be sure to ask your doctor or pharmacists about supplements and drug interactions especially if you are adding a new supplement or prescription drug.
Ginseng – used to increase energy, resistance to stress.
Hypoglycemic drugs – Ginseng also lowers blood sugar.
Furosemide – decreased diuretic effect.
Digoxin – may increase serum digoxin concentrations.
Monoamine oxidase inhibitors – headache, visual hallucinations, tremor, manic episodes.
Anticoagulants, antiplatelet agents – decreases effectiveness of Warfarin.
Estrogens – increases effect.
Corticosteroids – increases effect.
Drugs that cause gynecomastia (breast enlargement) – Ginseng contains estrone, estradiol, estriolm so it has an additive estrogenic effect.
Garlic – often used to reduce cholesterol.
Anticoagulants, antiplatelet – inhibits platelet aggregation may have additive anticoagulant and/or antiplatelet effect
Hypoglycemic drugs – increases hypoglycemic effect
St. John’s Wort – used for depression
Antidepressants, Sympathomineticamines, Ma Huang, Pseudoephedrine (Sudafed), Yohimbine – this herb may have monamine oxidase inhibitor or selective serotonin reuptake inhibitor effects. Can cause hypertension (high blood pressure) crisis, serotonin syndrome.
Digoxin – reduces effectiveness
Iron – reduces iron absorption
Piroxicam and other photosensitizers – increase photosensitivity (increased sun sensitivity), avoid use with UV light
Valerian – used for sleep
Opiates, Alcohol, Barbiturates, CNS depressants – increases sedation effect
Chamomile – relaxation, mild sedative
Iron – may inhibit iron absorption
Anticoagulants – may interfere with drug effects
Yohimbe – used for impotence
Antihypertensives, Caffeine, Ephedrine, Ma Huang – taken with this herb my cause hypotension low blood pressure) hypertension (high blood pressure), tachycardia (very rapid heart beat).
Antidepressants and St. John’s Wort – may have monoamine oxidase inhibitor activity
source: Univserity of Michigan Health System
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